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| CHEMICAL INFORMATION | |||
|---|---|---|---|
| Name | Carbetocin | CAS No. | 37025-55-1 |
| CAT No. | YD0008 | Storage | 3 years -20°C powder |
| Formula | C45H69N11O12S | 2 years -80°C in solvent | |
| Molecular | 988.18 | Purity | GMP |
| Description | Carbetocin is an obstetric drug used to control postpartum hemorrhage and bleeding after giving birth. | ||
| In vitro | Carbetocin also called (Butyryl1,Tyr(Me)2)-Oxytocin, (Butyryl1,Tyr(Me)2)-1-Carbaoxytocin, an oxytocin (OT) analogue, is an oxytocin receptor agonist with a Ki of 7.1 nM. Carbetocin has high affinity to chimeric N-terminus (E1) of the oxytocin receptor (Ki=1.17 μM). Carbetocin has the potential for postpartum hemorrhage research. Carbetocin can crosse the blood-brain barrier and produces antidepressant-like activity via activation of oxytocin receptors in the CNS. | ||
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