Evans Blue Modification

Plasma protein-based drug delivery is a good way to treat cancer; It has two main advantages: 1) Plasma protein-based drug carriers have higher permeability and retention in tumor cells;2) There are two types of plasma protein binding proteins that are overexpressed in the environment in which tumor cells are born. These two proteins play important roles in the absorption and retention of plasma proteins in various cells.

    Evans Blue (EB) is a kind of functional group with strong affinity for plasma proteins, it can be used to label plasma protein content and location in the body, Pharmacochemists can use this to assess permeability to the blood-brain barrier. EB can also be used for in vivo experiments; EB-bound plasma proteins can enter damaged or dead cells, but not healthy cells. Our company can conduct EB functional group modification and molecular imaging functional group modification for peptides active molecules at the same time, which can meet the frontier research of pharmaceutical chemists and pharmacologists.